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Children who wore contact lenses overnight as part of their orthokeratology regime developed corneal ulcers, resulting in corneal scarring and vision loss. According to a case study from China, appearing in the March issue of the American Academy of Ophthalmology's clinical, peer-reviewed journal, Ophthalmology, six children, nine to 14 years of age, were treated for bacterial eye infections after wearing the contact lenses eight to 12 hours each night.